Cancer migration is one of the worst things that can happen, and scientists have been tearing out hairs for years trying to figure out how to prevent this occurence. All that lost hair seems to have amounted to something major.. Check it out:
--------------------------------------------------
Clue To Stopping Breast-cancer Metastasis Discovered
ScienceDaily (Nov. 18, 2008) — If scientists knew exactly what a breast cancer cell needs to spread, then they could stop the most deadly part of the disease: metastasis. New research from the University of North Carolina at Chapel Hill School of Medicine takes a step in that direction.
Carol Otey, Ph.D. and UNC colleagues reduced the ability of breast cancer cells to migrate by knocking down the expression of a protein called palladin.
They also found higher levels of palladin in four invasive breast cancer cell lines compared to four non-invasive cell lines.
"This study shows that palladin may play an important role in the metastasis of breast cancer cells as they move out of the tumor and into the blood vessels and lymphatics to spread throughout the body," said Otey, associate professor of cell and molecular physiology.
Most women would never die from breast cancer if the cancer cells couldn't metastasize to the brain and bone marrow, Otey said. "To really make breast cancer a treatable disease, we have to be able to find a way to prevent or reduce the amount of metastasis."
Otey has been investigating palladin's role in cell movement since she discovered and named it in 2000.
Next she will examine a variety of samples of human tumors from a UNC tumor bank, to find out if the tumors from patients who had worse outcomes and more aggressive cancers contain higher levels of palladin.
The work was funded by the National Institutes of Health
Source: Science Daily; http://www.sciencedaily.com/releases/2008/11/081117153230.htm
--------------------------------------------------
Hopefully, the road ahead of this milestone will lead us to an effective solution!
W.
--------------------------------------------------
Clue To Stopping Breast-cancer Metastasis Discovered
ScienceDaily (Nov. 18, 2008) — If scientists knew exactly what a breast cancer cell needs to spread, then they could stop the most deadly part of the disease: metastasis. New research from the University of North Carolina at Chapel Hill School of Medicine takes a step in that direction.
Carol Otey, Ph.D. and UNC colleagues reduced the ability of breast cancer cells to migrate by knocking down the expression of a protein called palladin.
They also found higher levels of palladin in four invasive breast cancer cell lines compared to four non-invasive cell lines.
"This study shows that palladin may play an important role in the metastasis of breast cancer cells as they move out of the tumor and into the blood vessels and lymphatics to spread throughout the body," said Otey, associate professor of cell and molecular physiology.
Most women would never die from breast cancer if the cancer cells couldn't metastasize to the brain and bone marrow, Otey said. "To really make breast cancer a treatable disease, we have to be able to find a way to prevent or reduce the amount of metastasis."
Otey has been investigating palladin's role in cell movement since she discovered and named it in 2000.
Next she will examine a variety of samples of human tumors from a UNC tumor bank, to find out if the tumors from patients who had worse outcomes and more aggressive cancers contain higher levels of palladin.
The work was funded by the National Institutes of Health
Source: Science Daily; http://www.sciencedaily.com/releases/2008/11/081117153230.htm
--------------------------------------------------
Hopefully, the road ahead of this milestone will lead us to an effective solution!
W.
0 comments: